Mechanisms of molecular carcinogenesis. Volume 1 /

Divided into two volumes the work offers a so far unmatched broad and at the same time deep knowledge on molecular and cellular mechanisms of carcinogenesis and offers comprehensive insight into clinical, therapeutic and technological aspects. This 1st Volume presents tumor entities of the ocular sy...

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Bibliographic Details
Other Authors: Haybaeck, Johannes, (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, 2017.
Subjects:
Carcinogenesis > Molecular aspects.
elektronické knihy
electronic books
ISBN: 9783319536590
9783319536576
9783319536606
Physical Description: 1 online resource

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Table of contents

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024 7 |a 10.1007/978-3-319-53659-0  |2 doi 
035 |a (OCoLC)988079381  |z (OCoLC)988167745  |z (OCoLC)992535612  |z (OCoLC)992861814  |z (OCoLC)999454996  |z (OCoLC)1005773414  |z (OCoLC)1011796036  |z (OCoLC)1048131845  |z (OCoLC)1058366901  |z (OCoLC)1066467435  |z (OCoLC)1066472263  |z (OCoLC)1097102361  |z (OCoLC)1112537512 
245 0 0 |a Mechanisms of molecular carcinogenesis.  |n Volume 1 /  |c Johannes Haybaeck, editor. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references. 
505 0 |6 880-01  |a Preface; Contents; 1: The Endocannabinoid System in Carcinogenesis; 1.1 The Endocannabinoid System and Its Components; 1.2 The Endocannabinoid System and Cancer; 1.3 Receptors of the Endocannabinoid System Involved in Carcinogenesis; 1.4 Mechanisms of Anti-tumorigenic Effects by Cannabinoids/Endocannabinoids; 1.4.1 Apoptosis; 1.4.2 Autophagy; 1.4.3 Cell Proliferation and Cell Cycle Arrest; 1.4.4 Metastasis; 1.5 Anti-tumorigenic Effects of Cannabinoids/Endocannabinoids: Non-CB Receptor-Mediated; 1.6 Potential Pro-tumorigenic Effects of the Endocannabinoid System; 1.7 Synopsis. 
505 8 |a 2.3.1 MACC1 as Cancer Inducer2.3.2 MACC1 as Prognostic Marker; 2.3.3 MACC1 as Predictive Marker; 2.3.4 MACC1 as Druggable Target; 2.4 Outlook; References; 3: Axl and Its Mediated Signaling Axis in Cancer; 3.1 Axl Structure, Stimuli, and Expression; 3.1.1 Discovery and Structure of Axl; 3.1.2 Activation of Axl Signaling; 3.1.3 Axl Is Upregulated in Cancer; 3.2 Axl-Mediated Hallmarks of Cancer; 3.2.1 Axl Signaling in Cell Proliferation; 3.2.2 Antiapoptotic Functions of Axl Signaling; 3.2.3 Axl Signaling Induces Angiogenesis. 
505 8 |a 3.2.4 Axl Signaling Induces Epithelial-Mesenchymal Transition3.2.5 Axl Signaling in Cancer Metastasis; 3.2.6 Axl in Cancer Stemness; 3.3 Axl as Regulator of Drug Resistance in Cancer; References; 4: Insulin Signaling Linking Metabolism and Malignancy; 4.1 Introduction; 4.2 IGF1 in Cancer; 4.3 IGF2 in Cancer; 4.4 Insulin and IGF Signaling and Its Implication in Carcinogenesis; 4.4.1 Insulin Receptors, IGF Receptors, and Hybrid Receptors; 4.4.2 Insulin Receptor Substrates; 4.4.3 PI3K-Related Signaling; 4.4.4 MAPK-Related Signaling; References. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a Divided into two volumes the work offers a so far unmatched broad and at the same time deep knowledge on molecular and cellular mechanisms of carcinogenesis and offers comprehensive insight into clinical, therapeutic and technological aspects. This 1st Volume presents tumor entities of the ocular system, the thyroid organ, the oesophagus, gliomas, non-glial brain tumors, head and neck as well as lung cancer. In addition it also discusses in-depth potential novel molecular players and the role of stem cells as well as the endocannabinoid system in carcinogenesis, it furthermore explains tumor metabolism components and signaling pathways. Each of the chapters discusses potential therapeutic strategies and novel drug targets. The book addresses basic scientists and medical researchers interested in translational cancer research. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Carcinogenesis  |x Molecular aspects. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Haybaeck, Johannes,  |e editor. 
776 0 8 |i Printed edition:  |z 9783319536576 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-53659-0  |y Plný text 
992 |c NTK-SpringerBLS 
999 |c 97328  |d 97328 

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