Macrophages : origin, functions and biointervention

• Other Authors: Kloc, Malgorzata (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham, Switzerland : Springer, 2017.
• Series: Results and problems in cell differentiation ; 62.
• Subjects: Macrophages.; elektronické knihy; electronic books
• ISBN: 9783319540900; 9783319540894
• ISSN: 0080-1844 ;
• Physical Description: 1 online resource (x, 376 pages) : illustrations (some color)

This volume gives a state-of-the-art overview on macrophage functions in various invertebrate and vertebrate systems and diseases. It also covers various aspects of macrophage development and formation, behavior and response to nano- and biomaterials, the latter of which have become very important c...

Table of Contents:

• Preface; Abstract; Contents; Part I: Evolution, Origin and Fate of Macrophages; Chapter 1: Evolutionary Aspects of Macrophages Polarization; 1.1 Introduction; 1.2 Macrophage Polarization in Mammals; 1.3 Evolutionary Conservation of M1/M2-Like Functional Heterogeneity; 1.3.1 Bony Fish; 1.3.2 Amphibians; 1.3.2.1 Macrophage Polarization During X. laevis Antiviral Responses; 1.3.2.2 Macrophage Polarization During X. laevis Antibacterial Responses; 1.4 Conclusion; References.
• Chapter 2: Development and Functional Differentiation of Tissue-Resident Versus Monocyte-Derived Macrophages in Inflammatory R ... 2.1 Introduction; 2.2 Heterogeneity of Circulating Monocytes and Tissue-Resident Macrophages; 2.3 Origin of Macrophages; 2.3.1 Monocytes and moMphi Development: Definitive/Adult Hematopoiesis; 2.3.2 trMphi Ontogeny: Primitive/Fetal Hematopoiesis; 2.4 trMphi Versus moMphi; 2.4.1 In Situ Macrophage Expansion/Proliferation Versus Monocyte Recruitment; 2.4.2 Are moMphi and trMphi Phenotypically Distinguishable?; 2.4.3 Are moMphi and trMphi Functionally Interchangeable?
• 2.5 ConclusionsReferences; Chapter 3: Hofbauer Cells: Placental Macrophages of Fetal Origin; 3.1 Hofbauer Cell Definition and Origins; 3.2 The Biological Function of Hofbauer Cells; 3.3 Hofbauer Cells in Obstetric Complications; 3.4 Approaches for Studying Hofbauer Cells: Strengths and Potential Pitfalls; 3.5 Conclusions; References; Chapter 4: Mesenchymal Stem Cells Direct the Immunological Fate of Macrophages; 4.1 Introduction; 4.2 The Interplay Between Mesenchymal Stem Cells and Macrophages in Tissue Repair.
• 4.3 The Interplay Between Mesenchymal Stem Cells and Macrophages in Immune Tolerance4.4 Mesenchymal Stem Cells Promote Tumor Progression Through Macrophages; 4.5 Conclusions; References; Chapter 5: Monocyte/Macrophage: NK Cell Cooperation-Old Tools for New Functions; 5.1 Introduction; 5.2 Origin of Macrophages and NK Cells; 5.2.1 Macrophage Differentiation in Vertebrates and Invertebrates; 5.2.2 The Evolutionary Roots of Natural Killer Cells; 5.3 Phagocytosis; 5.3.1 Receptors Used in Phagocytosis; 5.4 Phenotypes of Vertebrate Macrophages; 5.4.1 Classification of Macrophages.
• 5.4.2 Plasticity and Polarization of Macrophages5.4.3 Polarization of Human Macrophages; 5.4.4 Molecular Mechanisms Underlying the Polarization of Macrophages; 5.5 Natural Killer Cells; 5.5.1 Definition and Classification; 5.5.2 Human NK Cell Population; 5.5.3 Origin and Development of NK Cells; 5.5.4 NK Licensing/Education Mechanisms; 5.5.5 Innate Memory NK Cells; 5.5.6 NK Cell Receptors; 5.5.6.1 Killer Cell Immunoglobulin-Like Receptors; 5.5.6.2 Natural Cytotoxicity Receptors; 5.5.6.3 C-Type Lectin-Like Receptors; 5.5.6.4 Fc Receptor CD16; 5.5.6.5 Co-activating Receptors.