Computational psychiatry : a systems biology approach to the epigenetics of mental disorders

This book explores mental disorders from a uniquely evolutionary perspective. Although there have been many attempts to mathematically model neural processes and, to some extent, their dysfunction, there is very little literature that models mental function within a sociocultural, socioeconomic, and...

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Bibliographic Details
Main Author Wallace, Rodrick (Author)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Springer, 2017.
Subjects
Online AccessFull text
ISBN9783319539102
9783319539096
Physical Description1 online resource (xii, 236 pages) : illustrations

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100 1 |a Wallace, Rodrick,  |e author. 
245 1 0 |a Computational psychiatry :  |b a systems biology approach to the epigenetics of mental disorders /  |c Rodrick Wallace. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2017. 
300 |a 1 online resource (xii, 236 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a Preface; Contents; 1 Consciousness, Crosstalk, and the Mereological Fallacy; 1.1 Introduction; 1.2 Some Cognitive Global Broadcasts; Immune System; Tumor Control; Wound Healing; Gene Expression; Sociocultural Cognition; 1.3 Animal Consciousness; 1.4 Cognition as ``Language''; 1.5 No Free Lunch; 1.6 Multiple Broadcasts, Punctuated Detection; 1.7 Metabolic Constraints; 1.8 Environmental Signals; 1.9 Dynamic ``Regression Models''; 1.10 Phase Transition Approaches; Basic Ideas; Kadanoff Theory; Other Versions of the Kadanoff Model; 1.11 The Rate Distortion Approach; Some Formalism; A Simple Model. 
505 8 |a A Less Simple ModelThe Index Theorem Attack; 1.12 Discussion and Conclusions; References; 2 Cultural Epigenetics: On the Missing Heritabilityof Complex Diseases; 2.1 Introduction; Mental Disorders and Culture; 2.2 A Cognitive Paradigm for Gene Expression; 2.3 Models of Development; 2.4 Tunable Epigenetic Catalysis; 2.5 The Groupoid Free Energy; Spontaneous Symmetry Breaking; The Groupoid Atlas; 2.6 ``Phase Change'' and the Developmental Holonomy Groupoid in Phenotype Space; 2.7 Holonomy on the Manifold of Dual Information Sources; Basic Structure; ``Coevolutionary'' Development. 
505 8 |a 2.8 Rate Distortion ModelsThe Rate Distortion Theorem; Rate Distortion Dynamics; Rate Distortion Coevolutionary Dynamics; 2.9 Expanding the Mathematical Approach; 2.10 Discussion; References; 3 Western Atomism and Its Culture-Bound Syndromes; 3.1 Introduction; 3.2 Western Atomistic Economics; 3.3 Cognition as an Information Source; 3.4 Environment as an Information Source; 3.5 Interacting Information Sources; 3.6 Crosstalk Topologies; 3.7 Punctuated Critical Phenomena; 3.8 Discussion and Conclusions; References; 4 Environmental Induction of Neurodevelopmental Disorders; 4.1 Introduction. 
505 8 |a 4.2 A Control Theory Model4.3 A ``Cognitive'' Model; 4.4 The Mitochondrial Connection; 4.5 Discussion and Conclusions; References; 5 Sleep, Psychopathology, and Culture; 5.1 Introduction; 5.2 Reaction Rate; 5.3 The Data Rate Theorem; 5.4 Rate Distortion Dynamics; 5.5 The Sleep Cycle: An Optimization Model; 5.6 Transition Dynamics; 5.7 Cultural Catalysis of the Sleep Cycle; 5.8 Environmental Induction of Sleep Disorders; 5.9 Chronic Dysfunctions of the Sleep Cycle; 5.10 Discussion and Conclusions; References; 6 Embodied Cognition and Its Disorders; 6.1 Introduction; 6.2 The Data Rate Theorem. 
505 8 |a 6.3 Cognition as an Information Source6.4 Environment as an Information Source; 6.5 Body Dynamics and Culture as Information Sources; 6.6 Interacting Information Sources; 6.7 Simple Regulation; 6.8 Extending the Data Rate Theorem; 6.9 Another Picture; 6.10 Large Deviations and Epileptiform Disorders; 6.11 Ground State Collapse 1: Anxiety/Depression Analogs; 6.12 Ground State Collapse 2: Obsessive Compulsive Disorders; 6.13 Topological Dysfunctions: Autism Spectrum and Schizophreniform Analogs; 6.14 Discussion and Conclusions; References; 7 Tools for the Future: Hidden Symmetries. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book explores mental disorders from a uniquely evolutionary perspective. Although there have been many attempts to mathematically model neural processes and, to some extent, their dysfunction, there is very little literature that models mental function within a sociocultural, socioeconomic, and environmental context. Addressing this gap in the extant literature, this book explores essential aspects of mental disorders, recognizing the ubiquitous role played by the exaptation of crosstalk between cognitive modules at many different scales and levels of organization, the missing heritability of complex diseases, and cultural epigenetics. Further, it introduces readers to valuable control theory tools that permit the exploration of the environmental induction of neurodevelopmental disorders, as well as the study of the synergism between culture, psychopathology and sleep disorders, offering a distinctively unique resource. 
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650 0 |a Psychiatry. 
650 0 |a Systems biology. 
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