Next generation antibody drug conjugates (ADCs) and immunotoxins

This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introd...

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Bibliographic Details
Other Authors: Grawunder, Ulf, (Editor), Barth, Stefan, (Editor)
Format: eBook
Language: English
Published: Cham : Springer, 2017.
Series: Milestones in drug therapy.
Subjects:
imunofarmakologie
monoklonální protilátky
onkologie
farmakoterapie
immunopharmacology
monoclonal antibodies
oncology
pharmacotherapy
elektronické knihy
sborníky
electronic books
papers of several authors
ISBN: 9783319468778
9783319468754
Physical Description: 1 online resource

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072 7 |a 616  |x Patologie. Klinická medicína  |2 Konspekt  |9 14 
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080 |a (082)  |2 MRF 
245 0 0 |a Next generation antibody drug conjugates (ADCs) and immunotoxins /  |c Ulf Grawunder, Stefan Barth, editors. 
264 1 |a Cham :  |b Springer,  |c 2017. 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Milestones in drug therapy 
504 |a Includes bibliographical references and index. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book describes the newest developments in antibody drug conjugates and immunotoxins, paving their way to clinical application. Lessons learned from the current state of the art are used to further improve our understanding of their mechanisms of action and off target activities. The book introduces scientists to all of the prerequisites that must be properly addressed, including identification of the right target, specific traits of target binding antibodies, proper selection of the toxic payload, internalization induced by binding, and next generation conjugation and linker technologies. These knowledge-based, revolutionary new drug principles will form the cornerstone of the future standard of care and will lead to major advances in application, as well as improved quality of life and patient survival rates. This book will be of interest to biotech companies and researchers working in the fields of immunology, pharmacology, and oncology.- Resumé vydavatel 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 7 |a imunofarmakologie  |2 czenas  |7 ph121047 
650 0 7 |a monoklonální protilátky  |2 czenas  |7 ph265700 
650 0 7 |a onkologie  |2 czenas  |7 ph123742 
650 0 7 |a farmakoterapie  |2 czenas  |7 ph134781 
650 0 9 |a immunopharmacology  |2 eczenas 
650 0 9 |a monoclonal antibodies  |2 eczenas 
650 0 9 |a oncology  |2 eczenas 
650 0 9 |a pharmacotherapy  |2 eczenas 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 7 |a sborníky  |7 fd163935  |2 czenas 
655 9 |a electronic books  |2 eczenas 
655 9 |a papers of several authors  |2 eczenas 
700 1 |a Grawunder, Ulf,  |e editor. 
700 1 |a Barth, Stefan,  |e editor. 
776 0 8 |i Print version:  |t Next generation antibody drug conjugates (ADCs) and immunotoxins.  |d Cham : Springer, 2017  |z 9783319468754  |z 3319468758  |w (OCoLC)957509009 
830 0 |a Milestones in drug therapy. 
856 4 0 |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-3-319-46877-8  |y Plný text 
942 |2 udc 
992 |c NTK-SpringerBLS 

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