Organ regeneration based on developmental biology
This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerati...
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| Other Authors: | |
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| Format: | eBook |
| Language: | English |
| Published: |
Singapore :
Springer,
2017.
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| Subjects: | |
| ISBN: | 9789811037689 9789811037665 |
| Physical Description: | 1 online resource (xiii, 257 pages) : illustrations (some color) |
Cover
Table of contents
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| 020 | |a 9789811037689 |q (electronic bk.) | ||
| 020 | |z 9789811037665 |q (print) | ||
| 024 | 7 | |a 10.1007/978-981-10-3768-9 |2 doi | |
| 024 | 8 | |a 10.1007/978-981-10-3 | |
| 035 | |a (OCoLC)980875014 |z (OCoLC)981616317 |z (OCoLC)981847430 |z (OCoLC)984855968 |z (OCoLC)999420368 |z (OCoLC)1005756199 |z (OCoLC)1011787535 |z (OCoLC)1048186214 |z (OCoLC)1066597087 |z (OCoLC)1105180223 | ||
| 245 | 0 | 0 | |a Organ regeneration based on developmental biology / |c edited by Takashi Tsuji, editor. |
| 264 | 1 | |a Singapore : |b Springer, |c 2017. | |
| 300 | |a 1 online resource (xiii, 257 pages) : |b illustrations (some color) | ||
| 336 | |a text |b txt |2 rdacontent | ||
| 337 | |a počítač |b c |2 rdamedia | ||
| 338 | |a online zdroj |b cr |2 rdacarrier | ||
| 506 | |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty | ||
| 520 | |a This book reviews three-dimensional (3D) stem cell culture and proof of concept for organ regeneration. The chapters present studies based on developmental biology but not tissue engineering using bio-degradative scaffolds. The ultimate goal of regenerative therapy, the next generation of regenerative therapy, is to develop fully functioning bioengineered 3D organs that can replace lost or damaged organs following disease, injury, or aging. Next-generation regenerative therapy will consist of organ-replacement regenerative therapy, which aims to reproduce reciprocal epithelial and epithelial interactions and epithelial and mesenchymal interactions that occur during embryogenesis. The book then discusses the generation of several 3D functional organs and organoids such as brain, inner ear, tooth, hair, salivary glands, lacrimal glands, gastrointestinal organs, kidney, liver, and lung. This work will appeal to a wide readership such as medical scientists, developmental biologists, clinicians, and patients. The volume provides valuable information and ideas to form a next-generation field of science. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Dedication; Preface; Contents; List of Contributors; Chapter 1: Telencephalic Tissue Formation in€3D Stem Cell Culture; 1.1 Introduction; 1.2 The Cerebral Cortex; 1.2.1 Development of€the€Cerebral Cortex In€Vivo; 1.2.2 3D Cortical Tissue Generation In€Vitro; 1.3 Ventralizing Telencephalic Tissues; 1.3.1 Development of€the€Ventral Telencephalon In€Vivo; 1.3.2 Development of€the€Ventral Telencephalon In€Vitro; 1.4 Dorsalizing Telencephalic Tissues; 1.4.1 Development of€Dorsomedial Telencephalic Structure In€Vivo; 1.4.2 Generation of€Dorsomedial Telencephalic Tissues In€Vitro. | |
| 505 | 8 | |a 1.5 Closing Remarks and€Future PerspectiveReferences; Chapter 2: Self-Organized Cerebellar Tissue from€Human Pluripotent Stem Cells and€Its Application to€Clinical Medicine; 2.1 Introduction; 2.2 Self-Organization of€Cerebellar Tissue from€hPSCs in€3D Culture; 2.2.1 Development of€Mammalian Cerebellum; 2.2.2 Attempt to€Generate Cerebellar Neurons from€PSCs; 2.2.3 Self-Induction of€Cerebellar Neurons from€hPSCs; 2.2.4 Self-Formation of€Polarized Cerebellar Structure; 2.3 Construction of€Human Cerebellar Disease Models with€Patient-Derived iPSCs; 2.4 Conclusion; References. | |
| 505 | 8 | |a Chapter 3: Functional Pituitary Tissue Formation Recapitulating Hypothalamus and€Pituitary Development Using ES/iPS Cells3.1 Introduction; 3.2 A Need for€Hypothalamus and€Adenohypophysis Regenerative Medicine; 3.3 Mouse Embryonic Stem Cells; 3.4 Pituitary Gland Embryology; 3.5 Three-Dimensional ES Cell Culture; 3.6 Induction of€Hypothalamic Neurons from€Mouse ES Cells; 3.7 Two-Layer Formation In€Vitro Is the€First Step of€Adenohypophysis Differentiation; 3.8 Self-Formation of€Rathke's Pouch; 3.9 Differentiation into Hormone-Producing Endocrine Cells; 3.10 Functionality of€Induced ACTH+ Cells. | |
| 505 | 8 | |a 3.11 Effect of€Transplantation into€Hypophysectomized Model Animals3.12 Adaptation to€Human ES/iPS Cell Culture; 3.13 Future Perspectives; References; Chapter 4: Inner Ear Organoids: Recapitulating Inner Ear Development in€3D Culture; 4.1 Introduction; 4.2 Inner Ear Development; 4.2.1 Formation of€the€Preplacodal Region; 4.2.2 Formation of€the€Otic Epibranchial Placode Domain; 4.2.3 Formation of€the€Otic Placode; 4.3 Generation of€Inner Ear Organoids; 4.3.1 Formation of€Nonneural Ectoderm (NNE); 4.3.2 Formation of€the€Preplacodal Region (PPR); 4.3.3 Formation of€the€Otic Placode. | |
| 505 | 8 | |a 4.3.4 Self-Guided Differentiation to€the€Inner Ear Sensory Epithelium4.3.5 Morphologic and€Functional Analysis of€Inner Ear Sensory Epithelia; 4.4 Potential Applications and€Limitations; References; Chapter 5: Functional Tooth Regeneration; 5.1 Introduction; 5.2 Tooth Organogenesis; 5.3 Tissue Repair and€Engineering by€Using Dental Tissue-ƯDerived Stem Cells and€Cytokines; 5.3.1 Stem-Cell Therapy; 5.3.1.1 Dentin-Pulp Tissue Repair; 5.3.1.2 Periodontal Tissue Repair; 5.3.2 Cytokine Approach; 5.3.3 Bioengineered Root Regeneration by€Tissue Engineering Technology. | |
| 590 | |a SpringerLink |b Springer Complete eBooks | ||
| 650 | 0 | |a Regenerative medicine. | |
| 650 | 0 | |a Organs (Anatomy) | |
| 655 | 7 | |a elektronické knihy |7 fd186907 |2 czenas | |
| 655 | 9 | |a electronic books |2 eczenas | |
| 700 | 1 | |a Tsuji, Takashi, |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Organ regeneration based on developmental biology. |d Singapore : Springer, 2017 |z 9811037663 |z 9789811037665 |w (OCoLC)967561070 |
| 856 | 4 | 0 | |u https://proxy.k.utb.cz/login?url=https://link.springer.com/10.1007/978-981-10-3768-9 |y Plný text |
| 992 | |c NTK-SpringerBLS | ||
| 999 | |c 97252 |d 97252 | ||
| 993 | |x NEPOSILAT |y EIZ | ||
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