rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Signaling-mediated control of cell division
    sub title: from oogenesis to oocyte-to-embryo development
  name:
    name part: Arur, Swathi
    role:
      role term: editor.
  type of resource: text
  genre: elektronické knihy
  genre: sborníky
  genre: electronic books
  genre: papers of several authors
  origin info:
    place:
      place term: sz
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: remote
    extent: 1 online resource
  abstract: This volume covers the current knowledge base on the role of signaling and environmental pathways that control the normal development of germline stem cells, meiotic progression of oocytes, events of oocyte maturation and fertilization, and the birth of an embryo. Germ cells are uniquely poised to sustain life across generations through the fusion of oocyte and sperm. Because of the central importance of germ cells to life, much work has been dedicated to obtaining a clear understanding of the molecular and signaling events that control their formation and maintenance. Germ cells are set aside from somatic cells in the embryo and go through specialized meiotic cell cycles as the animal matures. These cell cycles are interspersed with long periods of arrest. In human females, meiosis I is initiated in the fetus. At birth, oocytes are arrested in meiosis I; after puberty, every month an oocyte initiates meiosis II ovulation. Upon sperm availability these cells are fertilized, generate an embryo, and the cycle-of-life continues. During meiotic I progression and arrest, the fitness of oocytes and their progeny are likely influenced by environmental cues and signaling pathways. A lot of recent work has focused on understanding the mechanisms that regulate oocyte fitness and quality in humans and vertebrates. Much of our understanding on the events of meiosis I and germline stem cell populations comes from work in invertebrates, wherein the germline stem cells produce oocytes continuously through adult development. In both inverbrates and vertebrates nutritional and signaling pathways control the regulation of stem cells in such a manner so as to couple production of gametes with the nutritional availability. Additionally, mature oocytes arrest both in meiosis I and meiosis II, and signaling and nutritional pathways have been shown to regulate their formation, and maintenance, such that despite long periods of arrest, the oocyte quality is assured and errors in chromosome…
  target audience: specialized
  note: Swathi Arur, editor.
  note: Includes index.
  note: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  note: Includes bibliographical references and index.
  subject:
    topic: pohlavní buňky
  subject:
    topic: kmenové buňky
  subject:
    topic: buněčný cyklus
  subject:
    topic: cytofyziologie
  subject:
    topic: genová exprese
  subject:
    topic: embryologie člověka
  subject:
    topic: germ cells
  subject:
    topic: stem cells
  subject:
    topic: cell cycle
  subject:
    topic: cytophysiology
  subject:
    topic: gene expression
  subject:
    topic: human embryology
  classification: 611.013.1
  classification: 591.463.1+591.465.1
  classification: 602.9
  classification: 576.36
  classification: 612.014.3
  classification: 611.013
  classification: (0.034.2:08)
  classification: (082)
  related item:
    title info:
      title: Signaling-mediated control of cell division
    origin info:
      publisher: Cham, Switzerland : Springer, 2017
    identifier: (OCoLC)953709713
  related item:
    title info:
      title: Results and problems in cell differentiation ; v. 59
  identifier: 9783319448206
  identifier: 9783319448190
  identifier: https://proxy.k.utb.cz/login
  access condition: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  record info:
    record content source: N$T
    record creation date: 170302
    record change date: 20251008101049.0
    record identifier: 97210
    language of cataloging:
      language term: eng