Cartilage regeneration

This book focuses on cartilage defects and new mesenchymal stem cell-based treatments for their repair and regeneration. Early chapters provide a review of current etiological findings and repair methods of cartilage defects. The next chapters discuss fundamental concepts and features of MSCs, inclu...

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Bibliographic Details
Other Authors Lin, Yunfeng (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham, Switzerland : Humana Press, 2017.
SeriesStem cell biology and regenerative medicine.
Subjects
Online AccessFull text
ISBN9783319516172
9783319516165
Physical Description1 online resource

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Table of Contents:
  • Chapter 1: Application of€Stem Cells and€the€Factors Influence Their Differentiation in€Cartilage Tissue Engineering; 1.1 Introduction; 1.2 Embryonic Stem Cells; 1.3 Mesenchymal Stem Cells; 1.3.1 Different Sources of€Mesenchymal Stem Cells; 1.3.1.1 Bone Marrow Derived Stem Cells; 1.3.1.2 Adipose Tissue-Derived Stromal Cells; 1.3.1.3 Synovial-Derived Stem Cells; 1.3.1.4 Other Sources of€MSCs; 1.3.2 Comparison Between€Different MSCs in€Cartilage Tissue Engineering; 1.4 Other Kinds of€Stem Cells; 1.4.1 Induced Pluripotent Cells; 1.4.2 Cartilage Progenitor Cells.
  • 1.5 The Factors Influence the€Differentiation of€Stem Cells1.5.1 Co-culture; 1.5.2 Hypoxia; 1.5.3 High-Density Microenvironment; 1.5.4 Growth Factors; 1.5.5 Other Factors Influencing the€Differentiation of€Stem Cells; 1.6 Conclusion; References; Chapter 2: Application of€Scaffold Materials in€Cartilage Tissue Engineering; 2.1 Introduction; 2.2 Ideal Scaffold; 2.3 Materials for€the€Preparation of€Scaffold; 2.3.1 Collagen; 2.3.2 Gelatin; 2.3.3 Hyaluronan; 2.3.4 Fibrin; 2.3.5 Silk Fibers; 2.3.6 Synthetic Polymers; 2.3.7 Acellular Cartilage Matrix; 2.3.8 Polyhydoxyalkanoates (PHA) Family.
  • 3.4 Nano-patterns3.4.1 Nano-patterns Affect Cell Adhesion, Proliferation and€Migration; 3.4.2 Nano-patterns Affect Cell Differentiation; 3.5 Irregular Patterns-Roughness; 3.6 Stiffness; 3.7 Conclusion; References; Chapter 4: Electrospun Fibrous Scaffolds for€Cartilage Tissue Regeneration; 4.1 Electrospinning Materials in€Cartilage Tissue Engineering; 4.2 Topography of€Electrospun Fibrous Scaffold in€Cartilage Tissue Engineering; 4.3 Modifications of€Electrospun Fibrous Scaffold in€Cartilage Tissue Engineering; 4.4 New Electrospinning Approaches in€Cartilage Tissue Engineering.
  • 4.4.1 Dual-Electrospinning4.4.2 Coaxial Electrospinning; 4.4.3 "3D" Electrospinning; 4.5 Prospective; References; Chapter 5: The Research Advances of€Nanomaterials Inducing Osteogenic and€Chondrogenic Differentiation of€Stem Cells; 5.1 Introduction; 5.2 Various Nanomaterials Inducing Osteogenic and€Chondrogenic Differentiation of€Stem Cells; 5.2.1 Inorganic Nanomaterials; 5.2.1.1 Calcium Phosphate Nanocomposites; 5.2.1.2 Carbon Nanomaterials; 5.2.1.3 Silicon Nanoparticles; 5.2.1.4 Iron Oxide Nanoparticles; 5.2.1.5 Gold Nanoparticles; 5.2.1.6 Titanium Nanoparticles.