Free fatty acid receptors
"This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors...
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| Other Authors | , |
|---|---|
| Format | Electronic eBook |
| Language | English |
| Published |
Cham, Switzerland :
Springer,
[2017]
|
| Series | Handbook of experimental pharmacology ;
v. 236. |
| Subjects | |
| Online Access | Full text |
| ISBN | 9783319506937 9783319506920 |
| ISSN | 1865-0325 ; |
| Physical Description | 1 online resource (viii, 254 pages) : illustrations (chiefly color) |
Cover
Table of Contents:
- Ligands at free fatty acid receptor 1 (GPR40) / Takafumi Hara
- Ligands at the free fatty acid receptors 2/3 (GPR43/GPR41) / Graeme Milligan, Daniele Bolognini, Eugenia Sergeev
- Pharmacological tool compounds for the free fatty acid receptor 4 (FFA4/GPR120) / Steffen V.F. Hansen, Trond Ulven
- Application of GPCR structures for modelling of free fatty acid receptors / Irina G. Tikhonova
- Using biosensors to study free fatty acid receptor pharmacology and function / Brian D. Hudson
- Key questions for translation of FFA receptors: from pharmacology to medicines / Arthur T. Suckow, Celia P. Briscoe
- Polymorphic variation in FFA receptors: functions and consequences / Atsuhiko Ichimura
- The role and future of FFA1 as a therapeutic target / Julien Ghislain, Vincent Poitout
- Gut hormone regulation and secretion via FFA1 and FFA4 / Fiona M. Gribble, Eleftheria Diakogiannaki, Frank Reimann
- FFA2 and FFA3 in metabolic regulation / Cong Tang, Stefan Offermanns
- Anti-inflammatory and insulin-sensitizing effects of free fatty acid receptors / Junki Miyamoto, Mayu Kasubuchi, Akira Nakajima, Ikuo Kimura
- Free fatty acid receptors and cancer: from nutrition to pharmacology / Mandi M. Hopkins, Kathryn E. Meier.