Free fatty acid receptors

"This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors...

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Bibliographic Details
Other Authors: Milligan, Graeme, (Editor), Kimura, Ikuo, (Editor)
Format: eBook
Language: English
Published: Cham, Switzerland : Springer, [2017]
Series: Handbook of experimental pharmacology ; v. 236.
Subjects:
ISBN: 9783319506937
9783319506920
Physical Description: 1 online resource (viii, 254 pages) : illustrations (chiefly color)

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020 |a 9783319506937  |q (electronic bk.) 
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024 7 |a 10.1007/978-3-319-50693-7  |2 doi 
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245 0 0 |a Free fatty acid receptors /  |c Graeme Milligan, Ikuo Kimura, editors. 
264 1 |a Cham, Switzerland :  |b Springer,  |c [2017] 
264 4 |c ©2017 
300 |a 1 online resource (viii, 254 pages) :  |b illustrations (chiefly color) 
336 |a text  |b txt  |2 rdacontent 
336 |a statický obraz  |b sti  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Handbook of experimental pharmacology,  |x 1865-0325 ;  |v volume 236 
504 |a Includes bibliographical references and index. 
505 0 |a Ligands at free fatty acid receptor 1 (GPR40) / Takafumi Hara -- Ligands at the free fatty acid receptors 2/3 (GPR43/GPR41) / Graeme Milligan, Daniele Bolognini, Eugenia Sergeev -- Pharmacological tool compounds for the free fatty acid receptor 4 (FFA4/GPR120) / Steffen V.F. Hansen, Trond Ulven -- Application of GPCR structures for modelling of free fatty acid receptors / Irina G. Tikhonova -- Using biosensors to study free fatty acid receptor pharmacology and function / Brian D. Hudson -- Key questions for translation of FFA receptors: from pharmacology to medicines / Arthur T. Suckow, Celia P. Briscoe -- Polymorphic variation in FFA receptors: functions and consequences / Atsuhiko Ichimura -- The role and future of FFA1 as a therapeutic target / Julien Ghislain, Vincent Poitout -- Gut hormone regulation and secretion via FFA1 and FFA4 / Fiona M. Gribble, Eleftheria Diakogiannaki, Frank Reimann -- FFA2 and FFA3 in metabolic regulation / Cong Tang, Stefan Offermanns -- Anti-inflammatory and insulin-sensitizing effects of free fatty acid receptors / Junki Miyamoto, Mayu Kasubuchi, Akira Nakajima, Ikuo Kimura -- Free fatty acid receptors and cancer: from nutrition to pharmacology / Mandi M. Hopkins, Kathryn E. Meier. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a "This book highlights the important role free fatty acids (FFA) play as potential drug targets. While FFA have long been considered byproducts of cell metabolism, they are now recognized as ligands that regulate cell and tissue function via G-protein-coupled receptors. At least three receptors have been identified for which FFA appear to be the endogenous ligands"--Publisher's description. 
590 |a SpringerLink  |b Springer Complete eBooks 
650 0 |a Fatty acids  |x Receptors. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Milligan, Graeme,  |e editor. 
700 1 |a Kimura, Ikuo,  |e editor. 
776 0 8 |i Print version:  |t Free fatty acid receptors.  |d Cham, Switzerland : Springer, [2017]  |z 3319506927  |z 9783319506920  |w (OCoLC)962814957 
830 0 |a Handbook of experimental pharmacology ;  |v v. 236.  |x 0171-2004 
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