The actin cytoskeleton and bacterial infection

• Other Authors: Mannherz, Hans Georg, (Editor)
• Format: eBook
• Language: English
• Published: Cham, Switzerland : Springer, 2017.
• Series: Current topics in microbiology and immunology ; v. 399.
• Subjects: Actin.; Cytoskeleton.; elektronické knihy; electronic books
• ISBN: 9783319500478; 9783319500461
• Physical Description: 1 online resource (x, 242 pages) : illustrations
• ISSN: 0070-217X
• Access: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty

This volume describes the mechanisms which bacteria have created to secure their survival, proliferation and dissemination by subverting the actin cytoskeleton of host cells. Bacteria have developed a veritable arsenal of toxins, effector proteins and virulence factors that allow them to modify the properties of the intracellular actin cytoskeleton for their own purposes. Bacterial factors either modify actin directly as the main component of this part of the cytoskeleton or functionally subvert regulatory or signalling proteins terminating at the actin cytoskeleton. In short, this volume provides an overview of the various tricks bacteria have evolved to ℓ́ℓact on actinℓ́ℓ in order to hijack this essential host cell component for their own needs. As such, it will be of interest to scientists from many fields, as well as clinicians whose work involves infectious diseases.