Human retrotransposons in health and disease

This unique book explores the role of retrotransposons in human health and disease. The ability of retrotransposons to affect the structure of human genes is recognized since the late 80´s. However, the advances of deep-sequencing technologies have shed new light on the extent of retrotransposon-med...

Full description

Saved in:
Bibliographic Details
Other Authors Cristofari, Gael (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham : Springer, 2017.
Subjects
Transposons.
Human genetics.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319483443
9783319483436
Physical Description1 online resource

Cover

Table of Contents:
  • Retrotransposons and the Mammalian Germline
  • L1 regulation in Mouse and Human Germ Cells
  • Retrotransposon Contribution to Genomic Plasticity
  • The Mobilization of Processed Transcripts in Germline and Somatic Tissues
  • Neuronal Genome Plasticity: Retrotransposons, Environment and Disease
  • Activity of Retrotransposons in Stem Cells and Differentiated Cells
  • Environment, Cellular Signaling and L1 activity
  • Retrotransposon-derived Regulatory Regions and Transcripts in Stemness
  • Roles of Endogenous Retrovirus-encoded Syncytins in Human Placentation
  • Alu-Alu Recombinations in Genetic Diseases
  • Retrotransposon-driven Transcription and Cancer
  • LINE-1 retrotransposons as Neoplastic Biomarkers
  • Contribution of Retrotransposable Elements to Aging.

Similar Items