Antibiotics : targets, mechanisms and resistance
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| Corporate Author | |
|---|---|
| Other Authors | , , , |
| Format | Electronic eBook |
| Language | English |
| Published |
Weinheim, Germany :
Wiley-VCH,
[2014]
|
| Subjects | |
| Online Access | Full text |
| ISBN | 9783527659685 978-3-527-33305-9 |
| Physical Description | 1 online zdroj (xxiv, 549 stran) : ilustrace |
Cover
Table of Contents:
- A chemist's survey of different antibiotic classes
- Antibacterial discovery: problems and possibilities
- Impact of microbial natural products on antibacterial drug discovery
- Antibiotics and resistance: a fatal attraction
- Fitness costs of antibiotic resistance
- Inhibitors of cell-wall synthesis
- Inhibitors of bacetrial cell partitioning
- The membrane as a novel target site for antibiotics to kill persisting bacterial pathogens
- Bacterial membrane, a key for controlling drug influx and efflux
- Interference with bacterial cell-to-cell chemical signaling in development of new anti-infectives
- Recent developments in inhibitors of bacterial type IIA topoisomerases
- Antibiotics targeting bacterial RNA polymerase
- Inhibitors targeting riboswitches and ribozymes
- Targeting ribonuclease P
- Involvement of ribosome biogenesis in antibiotic functions, acquired resistance, and future opportunities in drug discovery
- Aminoacyl-tRNA synthetase inhibitors
- Antibiotics targeting translation initiation in prokaryotes
- Inhibitors of bacterial elongation factor EF-Tu
- Aminoglycoside antibiotics: structural decoding of inhibitors targeting the ribosomal decoding A site
- Reptidyltransferase inhibitors of the bacterial ribosome
- Antibiotics inhibiting the translocation step of protein elongation on the ribosome
- Antibiotics at the ribosomal exit tunnel
- selected structual aspects
- Targeting HSP70 to fight cancer and bad bugs: one and the same battle?