Microbial glycobiology structures, relevance and applications

• Other Authors: Moran, Anthony P., Holst, Otto, Brennan, Patrick J. Ph. D., Itzstein, Mark von
• Format: Electronic eBook
• Language: English
• Published: Amsterdam ; Boston : Academic Press/Elsevier, c2009.
• Edition: 1st ed.
• Subjects: Pathogenic microorganisms > Identification.; Glycomics.; elektronické knihy; electronic books
• ISBN: 9780080923246
• Physical Description: 1 online zdroj (xviii, 1000 p., [16] p. of plates) : ill. (some col.)

This book presents in an easy-to-read format a summary of the important central aspects of microbial glycobiology, i.e. the study of carbohydrates as related to the biology of microorganisms. Microbial glycobiology represents a multidisciplinary and emerging area with implications for a range of bas...

Table of Contents:

• Part I. Microbial glycolipids, glyoproteins and glycopolymersČ 1. Overview of the glycosylated components of the bacterial cell wallČČ 2. Bacterial cell wall envelope peptidoglycanČČ 3. Core oligosaccharide and lipid A components of lipopolysaccharidesČČ 4. O-Specific polysaccharides of Gram-negative bacteriaČČ 5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteriaČČ 6. Bacterial capsular polysaccharides and exopolysaccharidesČČ 7. Bacterial surface layer glycoproteins and "non-classical" secondary cell wall polymersČČ 8. Glycosylation of bacterial and archaeal flagellinsČČ 9. Glycosylated components of the mycobacterial cell wall: structure and functionČČ 10. Glycoconjugate structure and function in fungal cell wallsČČ 11. Cytoplasmic carbohydrate molecules: trehalose and glycogenČČ 12. Glycosylated compounds of parasitic protozoaČČ 13. Analytical approaches towards the structural characterization of microbial wall glycopolymersČČ 14.-Single-molecule characterization of microbial polysaccharidesČČ 15. Viral surface glycoproteins in carbohydrate recognition: structure and modelingČPart II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processesČ 16. Biosynthesis of bacterial peptidoglycanČČ 17. Biosynthesis and membrane assembly of lipid AČČ 18. Biosynthesis of O-antigen chains and assemblyČČ 19. Biosynthesis of cell wall teichoic acid polymersČČ 20. Biosynthesis and assembly of capsular polysaccharidesČČ 21. Biosynthesis of the mycobacterial cell envelope componentsČČ 22. Biosynthesis of fungal and yeast glycansČB. Chemical synthesisČČ 23. Chemical synthesis of bacterial lipid AČČ 24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharideČČ 25. Chemical synthesis of lipoichoic acid and derivativesČČ 26. Chemical synthesis of parasitic glycoconjugates and phosphoglycansČ Part III. Microbe-host glycosylated interactionsČČ 27.-Bacterial lectin-like interactions in cell recognition and adhesionČČ 28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactionsČČ 29. Sialic acid-specific microbial lectinsČČČ 30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interfaceČČ 31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptidesČČ 32. NOD receptor recognition of peptidoglycanČČ 33. Microbial interaction with mucus and mucinsČČ 34. Mannose-fucose recognition by DC-SIGNČČ 35. Host surfactant proteins in microbial recognitionČČ 36. T-cell recognition of microbial lipoglycans and glycolipidsČ Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevanceČČ 37. Extracellular polymeric substances in microbial biofilmsČČ 38. Physico-chemical properties of microbial glycopolymersČČ 39. Microbial biofilm-related polysaccharides in biofouling and corrosionČČ 40.-Microbial glycosylated components in plant diseaseČČB. Medical relevanceČČ 41. Antigenic variation of microbial surface glycosylated moleculesČČ 42. Phase variation of bacterial surface glycosylated molecules in immune evasionČČ 43. Molecular mimicry of host glycosylated structures by bacteriaČČ 44. Role of microbial glycosylation in host cell invasionČ Part V. Biotechnological and medical applicationsČČ 45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applicationsČČ 46. Industrial exploitation by genetic engineering of bacterial glycosylation systemsČČ 47. Glycomimetics as inhibitors in anti-infection therapyČČ 48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimeticsČČ 49. Immunomodulation by zwitterionic polysaccharidesČČ 50. Future potential of glycomics in microbiology and infectious diseasesČ