Antibacterial agents : chemistry, mode of action, mechanisms of resistance, and clinical applications

• Main Authors: Anderson, Rosaleen J. (Author), Groundwater, Paul W. (Author), Todd, Adam (Author), Worsley, Alan J. (Author)
• Corporate Author: John Wiley & Sons
• Format: eBook
• Language: English
• Published: Chichester : Wiley, 2012
• Subjects: antibakteriální látky; antibacterial agents; příručky; elektronické knihy; handbooks and manuals; electronic books
• ISBN: 9781118325421
• Physical Description: 1 online zdroj (xiv, 363 stran) : ilustrace (některé barevné)
• Access: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty univerzity

"Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated "lab-to-clinic" approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements."--Resumé vydavatele