Translational Anatomy and Cell Biology of Autism Spectrum Disorder

Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying cau...

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Bibliographic Details
Corporate Author SpringerLink (Online service)
Other Authors Schmeisser, Michael J. (Editor), Boeckers, Tobias M. (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham : Springer International Publishing : Imprint: Springer, 2017.
SeriesAdvances in Anatomy, Embryology and Cell Biology, 224
Subjects
Medicine.
Neurosciences.
Psychiatry.
Cell biology.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319524986
ISSN0301-5556 ;
DOI10.1007/978-3-319-52498-6
Physical DescriptionVIII, 211 p. 17 illus. in color. online resource.

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Table of Contents:
  • Anatomy and cell biology of autism spectrum disorder: Lessons from human genetics
  • Neuroanatomy and neuropathology of autism spectrum disorder in humans
  • Modelling autistic neurons with induced pluripotent stem cells
  • Modelling autistic features in mice using quantitative genetic approaches
  • Behavioural phenotypes and neural circuit dysfunctions in mouse models of autism spectrum disorder
  • Cerebellar and striatal pathologies in mouse models of autism spectrum disorder
  • The role of neurotrophic factors in mouse models of autism spectrum disorder: focus on Bdnf and Igf-1
  • The role of the oxytocin/arginine vasopressin system in animal models of autism spectrum disorder
  • Extracerebral dysfunction in animal models of autism spectrum disorder
  • Genetic and pharmacological reversibility of phenotypes in mouse models of autism spectrum disorder.

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