Translational Anatomy and Cell Biology of Autism Spectrum Disorder

Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying cau...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Schmeisser, Michael J. (Editor), Boeckers, Tobias M. (Editor)
Format: eBook
Language: English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Series: Advances in Anatomy, Embryology and Cell Biology, 224
Subjects:
Medicine.
Neurosciences.
Psychiatry.
Cell biology.
elektronické knihy
electronic books
ISBN: 9783319524986
Physical Description: VIII, 211 p. 17 illus. in color. online resource.

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020 |a 9783319524986 
024 7 |a 10.1007/978-3-319-52498-6  |2 doi 
245 1 0 |a Translational Anatomy and Cell Biology of Autism Spectrum Disorder /  |c edited by Michael J. Schmeisser, Tobias M. Boeckers. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2017. 
300 |a VIII, 211 p. 17 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Advances in Anatomy, Embryology and Cell Biology,  |x 0301-5556 ;  |v 224 
505 0 |a Anatomy and cell biology of autism spectrum disorder: Lessons from human genetics -- Neuroanatomy and neuropathology of autism spectrum disorder in humans -- Modelling autistic neurons with induced pluripotent stem cells -- Modelling autistic features in mice using quantitative genetic approaches -- Behavioural phenotypes and neural circuit dysfunctions in mouse models of autism spectrum disorder -- Cerebellar and striatal pathologies in mouse models of autism spectrum disorder -- The role of neurotrophic factors in mouse models of autism spectrum disorder: focus on Bdnf and Igf-1 -- The role of the oxytocin/arginine vasopressin system in animal models of autism spectrum disorder -- Extracerebral dysfunction in animal models of autism spectrum disorder -- Genetic and pharmacological reversibility of phenotypes in mouse models of autism spectrum disorder. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a Autism spectrum disorder (ASD) affects approximately 1 % of the human population and is characterized by a core symptomatology including deficits in social interaction and repetitive patterns of behaviour plus various co-morbidities. Although a lot of progress has been made to uncover underlying causes and mechanisms throughout the last decade, we are still at the very beginning to understand this enormously complex neurodevelopmental condition. This special volume is focused on translational anatomy and cell biology of ASD. International experts from the field including several members of the EU-AIMS initiative launched by the European Union to develop novel treatments for ASD have contributed chapters on several topics covering all crucial aspects of translational ASD research with a special emphasis on ASD model systems including stem cells and animals. Primary objective is to clarify how anatomical and cell biological phenotypes of ASD will help to translate basic mechanisms to clinical practice and to efficiently treat affected individuals in the near future. 
650 0 |a Medicine. 
650 0 |a Neurosciences. 
650 0 |a Psychiatry. 
650 0 |a Cell biology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Schmeisser, Michael J.  |e editor. 
700 1 |a Boeckers, Tobias M.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9783319524962 
830 0 |a Advances in Anatomy, Embryology and Cell Biology,  |x 0301-5556 ;  |v 224 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-52498-6  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 101668  |d 101668 

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