Gastrointestinal Stromal Tumors : Bench to Bedside

This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights o...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Scoggins, Charles R. (Editor), Raut, Chandrajit P. (Editor), Mullen, John T. (Editor)
Format: eBook
Language: English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Subjects:
Medicine.
Gastroenterology.
Surgery.
Surgical oncology.
elektronické knihy
electronic books
ISBN: 9783319426327
Physical Description: XI, 243 p. 61 illus., 24 illus. in color. online resource.

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Table of contents

LEADER 03972nam a22004095i 4500
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020 |a 9783319426327 
024 7 |a 10.1007/978-3-319-42632-7  |2 doi 
245 1 0 |a Gastrointestinal Stromal Tumors :  |b Bench to Bedside /  |c edited by Charles R. Scoggins, Chandrajit P. Raut, John T. Mullen. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2017. 
300 |a XI, 243 p. 61 illus., 24 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
505 0 |a Etiology/Epidemiology -- Pathology -- Molecular Genetics of GIST -- Pediatric GIST/Inheritable Disease -- Natural History -- Radiographic Imaging -- Endoscopic Evaluation -- Prognostic Factors for Localized Disease -- Management of Localized GIST: Non-Surgical Approaches-Surveillance and Endoscopic Resection -- Surgery for Localized GIST -- Minimally Invasive Surgery for GIST -- Neoadjuvant Rx and Surgical Consolidation -- Imatinib -- Management of Locally Advanced GIST -- Prognostic Factors for Advanced GIST -- Concepts of Targeted Therapy Management, Dose Escalation, Tailoring Therapy Based on Specific Mutations, Second Line Therapy -- Surgical Debulking of Metastatic GIST -- Liver Resection/Ablation of Metastatic GIST -- Palliative Care. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This textbook provides a comprehensive, state of the art review of this field, and will serve as a valuable resource for clinicians, surgeons and researchers with an interest in GIST. The book reviews new data about risk factors for the disease, profiles the new staging system for GIST, highlights our current understanding of genetic mutations that lead to GIST, and provides new perspectives about imaging of GIST tumors. For localized disease, a greater appreciation of organ-sparing approaches and the importance of preservation of gastrointestinal function is discussed in detail, and advances in surgical techniques are highlighted, including minimally invasive surgery. For metastatic disease, the molecular biology of GIST is reviewed in a detailed and understandable manner, including the data that has fostered novel targeted approaches that have revolutionized management. Several landmark trials have been published in the last few years and are placed in context with respect to current management. Integration of surgery and systemic therapy through consolidative approaches has yielded provocative data that promises to further advance the field, and major advances in this domain are also discussed. Gastrointestinal Stromal Tumors: Bench to Bedside will serve as a very useful resource for physicians and researchers dealing with, and interested in, this challenging malignancy. It provides a concise yet comprehensive summary of the current status of the field that will help guide patient management and stimulate investigative efforts. All chapters are written by experts in their fields and include the most up to date scientific and clinical information. 
650 0 |a Medicine. 
650 0 |a Gastroenterology. 
650 0 |a Surgery. 
650 0 |a Surgical oncology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Scoggins, Charles R.  |e editor. 
700 1 |a Raut, Chandrajit P.  |e editor. 
700 1 |a Mullen, John T.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9783319426303 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-42632-7  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 101626  |d 101626 
993 |x NEPOSILAT  |y EIZ 

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