Bone Morphogenetic Proteins: Systems Biology Regulators

This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Vukicevic, Slobodan. (Editor), Sampath, Kuber T. (Editor)
Format: eBook
Language: English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Series: Progress in Inflammation Research
Subjects:
Medicine.
Immunology.
Proteins.
Cytokines.
Growth factors.
Systems biology.
Cell biology.
elektronické knihy
electronic books
ISBN: 9783319475073
Physical Description: XII, 445 p. 43 illus., 32 illus. in color. online resource.

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Table of contents

LEADER 03456nam a22004575i 4500
001 101421
003 CZ-ZlUTB
005 20240914113411.0
006 m o d
007 cr nn 008mamaa
008 170315s2017 gw | s |||| 0|eng d
020 |a 9783319475073 
024 7 |a 10.1007/978-3-319-47507-3  |2 doi 
245 1 0 |a Bone Morphogenetic Proteins: Systems Biology Regulators /  |c edited by Slobodan Vukicevic, Kuber T. Sampath. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2017. 
300 |a XII, 445 p. 43 illus., 32 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Progress in Inflammation Research 
505 0 |a Introduction -- BMPs: Historic and Future Perspectives -- BMP - Biology -- BMPs in Development -- BMP signaling -- BMP Antagonists - Biology -- BMP and BMP Antagonists - Structure and Function -- BMPs in Orthopaedic Medicine: Promises and Challenges -- BMP6 and Bone Repair -- BMPs in Dental Medicine: Promises and Challenges -- BMPs in Spine -- BMPs in Articular Joints -- BMP Signaling & FOP -- BMP-7 Biology and its Therapeutic Utility for Chronic Kidney Diseases -- BMPs in Inflammation -- BMPs and Angiogenesis -- BMP Signaling in Iron Homeostasis -- BMP Signaling in Pulmonary Arterial Hypertension -- BMP Signaling and Cancer -- BMP Biology in Rare Diseases. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis and angiogenesis, including rare musculoskeletal disorders. BMPs, also referred to as growth and differentiation factors, are members of the TGF-beta superfamily and are highly conserved from fruit flies to mammals and are responsible for the formation of practically every organ during embryo development and involved in adult tissue injury and repair. BMPs establish their extracellular gradient by interacting with their respective antagonists and regulate their function through SMAD-dependent down-stream signaling effector genes. This volume is aimed at scientists and professionals dealing with metabolic disorders, nutrition, systems biology diseases, rare musculoskeletal conditions, and disorders related to iron metabolism, including anemia of chronic disease, hereditary hemochromatosis and beta thalassemia. 
650 0 |a Medicine. 
650 0 |a Immunology. 
650 0 |a Proteins. 
650 0 |a Cytokines. 
650 0 |a Growth factors. 
650 0 |a Systems biology. 
650 0 |a Cell biology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Vukicevic, Slobodan.  |e editor. 
700 1 |a Sampath, Kuber T.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9783319475059 
830 0 |a Progress in Inflammation Research 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-47507-3  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 101421  |d 101421 
993 |x NEPOSILAT  |y EIZ 

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