Patient-Derived Xenograft Models of Human Cancer

This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current appl...

Full description

Saved in:
Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Wang, Yuzhuo. (Editor), Lin, Dong. (Editor), Gout, Peter W. (Editor)
Format: eBook
Language: English
Published: Cham : Springer International Publishing : Imprint: Humana Press, 2017.
Series: Molecular and Translational Medicine,
Subjects:
ISBN: 9783319558257
Physical Description: XI, 204 p. 27 illus., 26 illus. in color. online resource.

Cover

Table of contents

LEADER 03267nam a22003975i 4500
001 101415
003 CZ-ZlUTB
005 20210209170621.0
006 m o d
007 cr nn 008mamaa
008 170629s2017 gw | s |||| 0|eng d
020 |a 9783319558257 
024 7 |a 10.1007/978-3-319-55825-7  |2 doi 
245 1 0 |a Patient-Derived Xenograft Models of Human Cancer /  |c edited by Yuzhuo Wang, Dong Lin, Peter W. Gout. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Humana Press,  |c 2017. 
300 |a XI, 204 p. 27 illus., 26 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
490 1 |a Molecular and Translational Medicine,  |x 2197-7852 
505 0 |a Introduction -- History and Evolution of PDX Cancer Models -- Establishment and Characterization of PDX Models -- Methods of Generating PDX Models -- Fidelity and Stability of PDX Models -- Applications of PDX Models -- Studies of Cancer Heterogeneity -- PDX and Cancer Stem Cells -- Modeling Cancer Metastasis -- Modeling Drug Resistance -- PDX and Biomarker Development -- PDX and Preclinical Drug Screening -- Co-clinical Trials and Personalized Cancer Therapy/Precision Medicine -- Epilogue -- Future Perspective. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book provides a comprehensive, state-of-the-art review of PDX cancer models. In separately produced chapters, the history and evolution of PDX models is reviewed, methods of PDX model development are compared in detail, characteristics of available established models are presented, current applications are summarized and new perspectives about use of PDX models are proposed. Each chapter is written by a world-renowned expert who is conducting cutting-edge research in the field. Each of the subsections provide a comprehensive review of existing literature addressing the particular topic followed by a conclusive paragraph detailing future directions. Extensive illustrations make this an interactive text. Patient-Derived Xenograft Models of Human Cancer will serve as a highly useful resource for researchers and clinicians dealing with, or interested in, this important topic. It will provide a concise yet comprehensive summary of the current status of the field that will help guide preclinical and clinical applications as well as stimulate investigative efforts. This book will propagate innovative concepts and prompt the development of ground-breaking technological solutions in this field. 
650 0 |a Medicine. 
650 0 |a Oncology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Wang, Yuzhuo.  |e editor. 
700 1 |a Lin, Dong.  |e editor. 
700 1 |a Gout, Peter W.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9783319558240 
830 0 |a Molecular and Translational Medicine,  |x 2197-7852 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-55825-7  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 101415  |d 101415