Hepatitis C Virus Treatment : Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance

This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resista...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Chayama, Kazuaki. (Editor)
Format: eBook
Language: English
Published: Singapore : Springer Singapore : Imprint: Springer, 2017.
Subjects:
Medicine.
Drug resistance.
Virology.
Hepatology.
elektronické knihy
electronic books
ISBN: 9789811024160
Physical Description: VII, 75 p. 23 illus., 14 illus. in color. online resource.

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Table of contents

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020 |a 9789811024160 
024 7 |a 10.1007/978-981-10-2416-0  |2 doi 
245 1 0 |a Hepatitis C Virus Treatment :  |b Highly Effective Therapy with Direct Acting Antivirals and Associated Viral Resistance /  |c edited by Kazuaki Chayama. 
264 1 |a Singapore :  |b Springer Singapore :  |b Imprint: Springer,  |c 2017. 
300 |a VII, 75 p. 23 illus., 14 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book introduces readers to Direct Acting Antiviral (DAAs) agents, newly developed drugs to treat chronic hepatitis C virus infection, which have an excellent anti-viral effect on virus replication. These drugs have been developed to enhance the effect of interferon and ribavirin, as the resistant strains against each drug have been described both in vitro and in vivo and the existences of naturally occurring variants have been reported. However, since the combination of different classes of DAAs is sufficient to completely eradicate the virus without the need for interferon or ribavirin, the current treatment regimen does not include interferon. Ribavirin is used in combination with sofosbuvir, a potent polymerase inhibitor, to enhance its antiviral effects. Hepatitis C Virus Treatment offers readers a comprehensive guide to hepatitis C; describing the resistance profiles against these drugs and shedding light on the difficulties involved in DAA therapy and the direction of future treatments, it will equip doctors to understand the essentials of treating the disease. It also describes in detail new and innovative DAA treatments, the effects of the agents, and the characteristics of resistance, providing cutting-edge information not only for hepatologists, but also for researchers, clinical residents, and medical students. 
650 0 |a Medicine. 
650 0 |a Drug resistance. 
650 0 |a Virology. 
650 0 |a Hepatology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Chayama, Kazuaki.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9789811024153 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-981-10-2416-0  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 101356  |d 101356 
993 |x NEPOSILAT  |y EIZ 

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