The Ageing Immune System and Health

The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity...

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Bibliographic Details
Corporate Author SpringerLink (Online service)
Other Authors Bueno, Valquiria (Editor), Lord, Janet M. (Editor), Jackson, Thomas A. (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham : Springer International Publishing : Imprint: Springer, 2017.
Subjects
Medicine.
Immunology.
Geriatrics.
Cell biology.
Aging.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319433653
DOI10.1007/978-3-319-43365-3
Physical DescriptionXII, 182 p. 19 illus., 11 illus. in color. online resource.

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Table of Contents:
  • 1. Introduction
  • 2. Innate Immune Response and Ageing (neutrophils, monocytes, dendritic cells, DAMPs, PAMPs
  • 3. Adaptive Immune Response and Aging (T and B lymphocytes, naïve, effector and memory phenotypes and functions)
  • 4. Modulatory/Suppressive Cells and Ageing (T regulatory cells, B regulatory cells, Myeloid Derived Suppressor Cells, Modulatory Neutrophils, M1 and M2 macrophages)
  • 5. Mucosal Immune System and Ageing
  • 6. Epigenetics and Ageing
  • 7. Cancer and Ageing
  • 8. Infections/Vaccination and Ageing
  • 9. Cytomegalovirus and immmunosenescence
  • 10. Frailty and Ageing
  • 11. Inflammation and Neurodegenerative Diseases and Ageing
  • 12. Effects of chronic inflammatory diseases (chronic kidney disease, rheumatoid arthritis, crohns disease etc) on the ageing of the immune system
  • 13. Interventions in Elderly focusing Immunosenescence (physical activity, nutrition, supplements).

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