The Ageing Immune System and Health

The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Bueno, Valquiria. (Editor), Lord, Janet M. (Editor), Jackson, Thomas A. (Editor)
Format: eBook
Language: English
Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
Subjects:
Medicine.
Immunology.
Geriatrics.
Cell biology.
Aging.
elektronické knihy
electronic books
ISBN: 9783319433653
Physical Description: XII, 182 p. 19 illus., 11 illus. in color. online resource.

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Table of contents

LEADER 03624nam a22004215i 4500
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020 |a 9783319433653 
024 7 |a 10.1007/978-3-319-43365-3  |2 doi 
245 1 4 |a The Ageing Immune System and Health /  |c edited by Valquiria Bueno, Janet M. Lord, Thomas A. Jackson. 
264 1 |a Cham :  |b Springer International Publishing :  |b Imprint: Springer,  |c 2017. 
300 |a XII, 182 p. 19 illus., 11 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
505 0 |a 1. Introduction -- 2. Innate Immune Response and Ageing (neutrophils, monocytes, dendritic cells, DAMPs, PAMPs -- 3. Adaptive Immune Response and Aging (T and B lymphocytes, naïve, effector and memory phenotypes and functions) -- 4. Modulatory/Suppressive Cells and Ageing (T regulatory cells, B regulatory cells, Myeloid Derived Suppressor Cells, Modulatory Neutrophils, M1 and M2 macrophages) -- 5. Mucosal Immune System and Ageing -- 6. Epigenetics and Ageing -- 7. Cancer and Ageing -- 8. Infections/Vaccination and Ageing -- 9. Cytomegalovirus and immmunosenescence -- 10. Frailty and Ageing -- 11. Inflammation and Neurodegenerative Diseases and Ageing -- 12. Effects of chronic inflammatory diseases (chronic kidney disease, rheumatoid arthritis, crohns disease etc) on the ageing of the immune system -- 13. Interventions in Elderly focusing Immunosenescence (physical activity, nutrition, supplements). 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a The present book intends to provide an update on immunosenescence and how deficiencies in the immune system contribute to a higher susceptibility to infections, decline in organ function, reduced vaccination responses, age-related disease and the ageing process itself, negatively affecting longevity. Our focus is on the main changes in immune system cells and their products occurring during the ageing process and the possible consequences for health and disease. This includes: discussion of the modulatory and/or suppressive mechanisms associated with the alterations in T regulatory cells, B regulatory cells and Myeloid Derived Suppressor cells; changes in the immune system observed in chronic neurodegenerative diseases, cancer, lung disease and frailty will also be discussed. Most importantly we provide recent literature information about possible interventions (focusing on physical activity) that could alleviate the negative effects of immunosenescence. The Ageing Immune System and Health is a comprehensive guide on the field intended to all physicians, researchers, professors and students interested on relationship between immune system, ageing and health. . 
650 0 |a Medicine. 
650 0 |a Immunology. 
650 0 |a Geriatrics. 
650 0 |a Cell biology. 
650 0 |a Aging. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
700 1 |a Bueno, Valquiria.  |e editor. 
700 1 |a Lord, Janet M.  |e editor. 
700 1 |a Jackson, Thomas A.  |e editor. 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9783319433639 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-3-319-43365-3  |y Plný text 
992 |c NTK-SpringerMED 
999 |c 101285  |d 101285 
993 |x NEPOSILAT  |y EIZ 

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