Ex Vivo Engineering of the Tumor Microenvironment

This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in un...

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Bibliographic Details
Corporate Author SpringerLink (Online service)
Other Authors Aref, Amir R. (Editor), Barbie, David (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham : Springer International Publishing : Imprint: Humana Press, 2017.
SeriesCancer Drug Discovery and Development,
Subjects
Online AccessFull text
ISBN9783319453972
ISSN2196-9906
DOI10.1007/978-3-319-45397-2
Physical DescriptionIX, 135 p. 18 illus., 17 illus. in color. online resource.

Cover

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505 0 |a 1.Introduction to Ex Vivo Cancer Models -- 2.Patient-derived Xenografts in Oncology -- 3.Organoid Culture: Applications in Development and Cancer -- 4. Microfluidics and future of cancer diagnostics -- 5.Advancing techniques and insights in circulating tumor cell (CTC) research -- 6.The Cancer Secretome -- 7.An overview of the tumor microenvironments and future of cancer therapy. . 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time. 
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