rdf-syntax-grammar
mods:
  schema location: http://www.loc.gov/mods/v3 http://www.loc.gov/standards/mods/v3/mods-3-2.xsd
  title info:
    title: Testicular Autoimmunity
    sub title: A Cause of Male Infertility
  name:
    name part: Itoh, Masahiro.
    role:
      role term: creator
    role:
      role term: author.
  name:
    name part: SpringerLink (Online service)
  type of resource: text
  genre: elektronické knihy
  genre: electronic books
  origin info:
    place:
      place term: ja
    date issued: 2017
    issuance: monographic
  language:
    language term: eng
  physical description:
    form: electronic
    reformatting quality: access
    form: remote
    extent: XVII, 232 p. 54 illus., 43 illus. in color. online resource.
  abstract: This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses "the immunological fragility of testis" with regard to male infertility, reviewing aut opsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals.
  table of contents: Chapter 1. Biological background of testicular autoimmunity -- Chapter 2. Microcircumstance for induction and prevention of testicular autoimmunity -- Chapter 3. Human testicular autoimmunity as a result of breakdown of testicular immune privilege -- Chapter 4. Testicular autoimmunity by immunization with testicular antigens alone in experimental animals -- Chapter 5. Testicular autoimmunity by the systemic treatment with immuno-potentiating agents in experimental animals -- Chapter 6. Testicular autoimmunity by local injury of the testis in experimental animals.-&a mp;n bsp; Chapter 7. Testicular autoimmunity in experimental animals induced by manipulation of the immune system -- Chapter 8. The future directions of testicular autoimmunity investigation.
  note: by Masahiro Itoh.
  note: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  subject:
    topic: Medicine
  subject:
    topic: Immunology
  subject:
    topic: Reproductive medicine
  subject:
    topic: Urology
  identifier: 9784431544609
  identifier: https://proxy.k.utb.cz/login
  access condition: Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty
  record info:
    record creation date: 170731
    record change date: 20251008112021.0
    record identifier: 100985