Testicular Autoimmunity : A Cause of Male Infertility

This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first re...

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Bibliographic Details
Main Author: Itoh, Masahiro. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Language: English
Published: Tokyo : Springer Japan : Imprint: Springer, 2017.
Subjects:
Medicine.
Immunology.
Reproductive medicine.
Urology.
elektronické knihy
electronic books
ISBN: 9784431544609
Physical Description: XVII, 232 p. 54 illus., 43 illus. in color. online resource.

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020 |a 9784431544609 
024 7 |a 10.1007/978-4-431-54460-9  |2 doi 
100 1 |a Itoh, Masahiro.  |e author. 
245 1 0 |a Testicular Autoimmunity :  |b A Cause of Male Infertility /  |c by Masahiro Itoh. 
264 1 |a Tokyo :  |b Springer Japan :  |b Imprint: Springer,  |c 2017. 
300 |a XVII, 232 p. 54 illus., 43 illus. in color.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a počítač  |b c  |2 rdamedia 
338 |a online zdroj  |b cr  |2 rdacarrier 
505 0 |a Chapter 1. Biological background of testicular autoimmunity -- Chapter 2. Microcircumstance for induction and prevention of testicular autoimmunity -- Chapter 3. Human testicular autoimmunity as a result of breakdown of testicular immune privilege -- Chapter 4. Testicular autoimmunity by immunization with testicular antigens alone in experimental animals -- Chapter 5. Testicular autoimmunity by the systemic treatment with immuno-potentiating agents in experimental animals -- Chapter 6. Testicular autoimmunity by local injury of the testis in experimental animals.-&a mp;n bsp; Chapter 7. Testicular autoimmunity in experimental animals induced by manipulation of the immune system -- Chapter 8. The future directions of testicular autoimmunity investigation. 
506 |a Plný text je dostupný pouze z IP adres počítačů Univerzity Tomáše Bati ve Zlíně nebo vzdáleným přístupem pro zaměstnance a studenty 
520 |a This book addresses various aspects of testicular autoimmunity. It has long been suspected that testicular autoimmunity could be one of the causes of idiopathic male infertility. However, it is very difficult to estimate the incidence of testicular autoimmunity in men, as most male patients first realize they are infertile when they start trying to conceive a child, and there is a possibility that their testes may already exhibit the end stage of testicular autoimmunity, in which lymphocytic inflammation and immunoglobulin deposition in their testes subsided long ago and only the spermatogenic disorder remains. Therefore, autopsy or biopsy for testicular tissues in men before the end stage of testicular autoimmunity and investigations using testicular autoimmunity model animals are needed to determine the epidemiology of testicular autoimmunity. Accordingly, the book discusses "the immunological fragility of testis" with regard to male infertility, reviewing aut opsy data in men and presenting experimental data using murine models of autoimmune orchitis that has been induced by immunizing with viable syngeneic testicular germ cells alone. Testicular autoimmunity in animals is also discussed. In summary, the book provides a wealth of valuable information, not only for researchers who are interested in immunologic male infertility, but also for clinical professionals who treat these patients at hospitals. 
650 0 |a Medicine. 
650 0 |a Immunology. 
650 0 |a Reproductive medicine. 
650 0 |a Urology. 
655 7 |a elektronické knihy  |7 fd186907  |2 czenas 
655 9 |a electronic books  |2 eczenas 
710 2 |a SpringerLink (Online service) 
776 0 8 |i Printed edition:  |z 9784431544593 
856 4 0 |u https://proxy.k.utb.cz/login?url=http://dx.doi.org/10.1007/978-4-431-54460-9  |y Plný text 
942 |2 udc 
992 |c NTK-SpringerMED 
993 |x NEPOSILAT  |y EIZ 

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