Increasing the Therapeutic Ratio of Radiotherapy

Current cancer therapies are focused on three general strategies: modifying intrinsic radiosensitivity via molecular targeting, manipulating microenvironmental factors to enhance tumor susceptibility to radiation, and improving delivery of radiation to critical tumor locations while sparing normal t...

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Bibliographic Details
Corporate Author SpringerLink (Online service)
Other Authors Tofilon, Philip J. (Editor), Camphausen, Kevin (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham : Springer International Publishing : Imprint: Humana Press, 2017.
SeriesCancer Drug Discovery and Development,
Subjects
Medicine.
Cancer research.
Drug resistance.
Radiotherapy.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319408545
ISSN2196-9906
DOI10.1007/978-3-319-40854-5
Physical DescriptionVIII, 280 p. 41 illus., 34 illus. in color. online resource.

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Table of Contents:
  • Part 1. Molecular Targets
  • 1. Improving the therapeutic ratio of radiotherapy by targeting the DNA Damage Response
  • 2. Receptor Tyrosine Kinases as Targets for Enhancing Tumor Radiosensitivity
  • 3. Histone Deacetylase Inhibitors and Tumor Radiosensitization
  • 4. Radioprotection as a Method to Enhance the Therapeutic Ratio of Radiotherapy
  • Part 2. Microenvironment
  • 5. Application of Functional Molecular Imaging in Radiation Oncology
  • 6. Remodeling the Irradiated Tumor Microenvironment: The 5th R of Radiobiology?
  • 7. Combining Radiotherapy and Immunotherapy: Emerging Preclinical Observations of Lymphocyte Costimulatory and Inhibitory Receptor Modulation
  • Part 3. Clinical
  • 8. Stereotactic Body Radiation Therapy (SBRT) or Alternative Fractionation Schedules
  • 9. Novel Imaging for Treatment Planning or Tumor Response
  • 10. Increasing the Therapeutic Efficacy of Radiotherapy Using Nanoparticles
  • Index.

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