Chemotherapy for Leukemia : Novel Drugs and Treatment

This book focuses on the latest progress in chemotherapy for leukemia and related diseases, including still-ongoing but promising studies. The effectiveness of treatment for chronic myeloid leukemia and acute promyelocytic leukemia has been dramatically improved in recent years. This improvement has...

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Bibliographic Details
Corporate Author SpringerLink (Online service)
Other Authors Ueda, Takanori (Editor)
Format Electronic eBook
LanguageEnglish
Published Singapore : Springer Singapore : Imprint: Springer, 2017.
Subjects
Online AccessFull text
ISBN9789811033322
DOI10.1007/978-981-10-3332-2
Physical DescriptionVIII, 361 p. 82 illus., 51 illus. in color. online resource.

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Table of Contents:
  • 1 An Overview
  • Part I Bcr-Abl Tyrosine Kinase Inhibitors (TKIs)
  • 2 Imatinib: Basic Results
  • 3 Imatinib: Clinical Pharmacology and Therapeutic Results
  • 4 Dasatinib, Nilotinib, Bosutinib, Ponatinib, and Other TKIs
  • Part II New Antibodies for Leukemia
  • 5 Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Basic Results
  • 6 Rituximab and Alemtuzumab for Chronic Lymphocytic Leukemia: Clinical Pharmacology and Therapeutic Results
  • 7 Inotuzumab Ozogamicin for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results
  • 8 Blinatumomab for Acute Lymphoblastic Leukemia: Clinical Pharmacology and Therapeutic Results
  • 9 Mogamulizumab in Adult T-cell Leukemia/Lymphoma
  • Part III Signaling inhibitors
  • 10. FLT3 inhibitors
  • Part IV Differentiating Agents
  • 11 Retinoic Acid, All-Trans Retinoic Acid (ATRA) and Tamibarotene
  • 12 The Molecular Basis of Arsenic Trioxide Treatment for Acute Promyelocytic Leukemia (APL)
  • 13 Arsenic Trioxide: Clinical Pharmacology and Therapeutic Results
  • Part V New Chemotherapeutic Agents Including Antimetabolite
  • 14 Nelarabine
  • 15 Forodesine
  • 16 Clofarabine: Structure, Mechanism of Action, and Clinical Pharmacology
  • 17 Clinical Use of Clofarabine for Adults and Children with Leukemia
  • 18 Re-Emerging Antimetabolites with Novel Mechanism of Action with Respect to Epigenetic Regulation: Basic Aspects
  • 19 Epigenetic Regulator, Re-Emerging Antimetabolites with Novel Mechanism of Action (Azacitidine and Decitabine): Clinical Pharmacology and Therapeutic Results
  • Part VI Therapy Targeting Leukemic Stem Cells
  • 20 Therapies Targeting Leukemic Stem Cells.