Neuroprotective Therapy for Stroke and Ischemic Disease

This book is a critical and comprehensive look at current state-of-the-art scientific and translational research being conducted internationally, in both academia and industry; it serves to address new ways to provide effective treatment to victims of ischemic and hemorrhagic stroke and other ischem...

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Bibliographic Details
Corporate Author SpringerLink (Online service)
Other Authors Lapchak, Paul A. (Editor), Zhang, John H. (Editor)
Format Electronic eBook
LanguageEnglish
Published Cham : Springer International Publishing : Imprint: Springer, 2017.
SeriesSpringer Series in Translational Stroke Research,
Subjects
Medicine.
Neurosciences.
Cardiology.
elektronické knihy
electronic books
Online AccessFull text
ISBN9783319453453
ISSN2363-958X
DOI10.1007/978-3-319-45345-3
Physical DescriptionXVII, 795 p. 105 illus., 71 illus. in color. online resource.

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Table of Contents:
  • Reflections on Neuroprotection Research and the Path Toward Clinical Success
  • Systematic review & meta-analysis: important tools in understanding
  • Neuroprotection is Technology, not Science
  • History of Experimental Stroke Research
  • History of Neuroprotection: Trials and Tribulations
  • Targeting PSD-95 As a Novel Approach in the Treatment of Stroke
  • ATP Sensitive Potassium Channels (KATP) Play a Role in Hypoxic Preconditioning against Neonatal Hypoxic-Ischemic Brain Injury
  • Targeting Oxidative Stress in Stroke
  • Nitrones, Old Fellows for New Therapies in Ischemic Stroke
  • Neuroprotective strategies via modulation of innate immune receptors
  • Harnessing the power of the human immune system via multi-omic immune profiling in stroke treatment and recovery
  • Polarization of microglia/macrophages in brain ischemia: relevance for stroke therapy
  • Endoplasmic Reticulum Stress: An Opportunity for Neuroprotective Strategies after Stroke
  • Effects of Neuroprotectants before and after stroke: Statins and Anti-Hypertensives
  • Toward Effective Combination Therapy and Pleiotropic Drugs
  • TRPM7 Channels as Potential Therapeutic Targets for Stroke Cholinergic Protection in Ischemic Brain Injury
  • Remote Ischemic Conditioning: A Highly Translatable Therapy for Acute Stroke
  • Hypothermia for Acute Ischemic Stroke
  • Modern endovascular treatment of ischemic disease
  • Cerebral Microbleeds and Thrombolysis for Acute Ischemic Stroke
  • Targeting pericytes and the microcirculation for ischemic stroke therapy
  • Thrombolytic and Endovascular Therapies for Acute Ischemic Stroke
  • Sonothrombolysis for acute ischemic stroke: a critical appraisal
  • Combination Therapy with Thrombolysis
  • Oxygen Carriers: Are they enough for cellular support?
  • A new paradigm in protecting ischemic brain: preserving the neurovascular unit before reperfusion
  • The right rodent for the job: infarct variability between strains and its impact on logistics of experimental animal studies
  • Rabbit Spinal Cord Ischemia Model for the Development of Neuroprotective Treatments
  • Stroke Sex Differences: from basic research to clinical trials
  • Unpuzzling the co-morbid type 2 diabetes and hypertension-related cognitive dysfunction and stroke
  • Sex Specific Factors in Stroke
  • Current Imaging Strategies for Patient Selection in Acute Ischemic Stroke Trials.

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