James Vaughn may refer to:
* Joseph Paul Franklin (1950–2013), American neo-Nazi and serial killer, born James Vaughn
* Hippo Vaughn (1888–1966), American baseball player, born James Leslie Vaughn
* James T. Vaughn (1925–2007), American politician and law enforcement officer
* James T. Vaughn Jr. (born 1949), American lawyer and judge
Provided by Wikipedia
